These can include nausea, vomiting, diarrhea, constipation, reflux, reduced appetite, and abdominal discomfort
It is reasonable to take both observations seriously as hypotheses, with two cautions: Phase 2 trials are smaller, and the trial populations are not identical to GLP-1 trial populations
Severe abdominal pain, persistent vomiting, dehydration, breathing problems, facial swelling, or other serious symptoms require prompt medical attention
That said, its important to note: there is no direct head-to-head clinical trial between Tirzepatide and Retatrutide yet
Many insurers still classify Ozempic as a "non-essential" or "lifestyle" drug when used for obesity, even though the American Medical Association and CDC recognize obesity as a chronic disease